The Rhesus Factors—II: Haemolytic Disease of the New-Born
نویسنده
چکیده
extreme lethargy, with enlargement of liver and spleen, and ensuing severe anaemia if the infant survives the first few days. Hampson (1928) reported a series of these cases with 80 per cent, mortality rate. The surviving infants were frequently found to have cirrhosis of the liver and neurological signs of basal ganglia damage, termed kernicterus. Congenital Anaemia is a rarer manifestation, with & higher survival rate. The anaemia, which is severe, is frequently hot recognized until the end of the first week and is often accompanied by little jaundice. It is now known that otherwise unexplained still-birth may also be a manifestation of this disease. Theories of Causation.?For many yeais spasmodic interest has been evoked in morbid reactions taking place between the mother and her foetus. Dienst (1908) suggested that "the mother is immunized by the blood of her foetus which might cause toxaemia
منابع مشابه
Rhesus haemolytic disease of the newborn: Postnatal management, associated morbidity and long-term outcome.
Rhesus haemolytic disease of the newborn can lead to complications such as hyperbilirubinaemia, kernicterus and anaemia. Postnatal management consists mainly of intensive phototherapy, exchange transfusion and blood transfusion. During the last decades, significant progress in prenatal care strategies for patients with Rhesus haemolytic disease has occurred. New prenatal management options have...
متن کاملDeaths from rhesus haemolytic disease in England and Wales in 1978: accuracy of records and assessment of anti-D prophylaxis.
All the death certificates for deaths in 1977 where haemolytic disease of the newborn (HDN) was the principal, an antecedent, or a contributory cause were obtained from the Office of Population Censuses and Surveys (OPCS). The hospital notes of all 54 of the live-born cases and all of the 101 stillbirths were also obtained. The cause of the death indicated by the notes was compared with the cau...
متن کاملThe Rhesus Danger. Its Medical, Moral and Legal Aspects
The author of this book writes with understandable bias because two of his children have died from haemolytic disease of the newborn, which is the gravest of the perils of the " Rhesus danger As the book is intended in part for the lay reader, this bias may be the cause of some unnecessary anxiety. The material is divided into two parts. The first section deals ably with the medical background ...
متن کاملRapid and Economical Rhesus Testing: A Trial of Chown's Capillary Tube Method.
Introduction It is now firmly established that immunization by the Rhesus factor plays a predominant part in the pathogenesis of haemolytic disease of the newborn (Levine and others, 1941a and b), and that treatment by early induction of labour and transfusion or exsanguination transfusion will reduce the mortality of affected infants to about one quarter of that found in an untreated series (D...
متن کاملFoetal haemoglobin in haemolytic disease of the newborn.
A difference in the proportions of foetal (Hb-F) and adult (Hb-A) haemoglobins between normal infants and those affected by haemolytic disease due to the rhesus factor was first reported by Jonxis (1948). His work was later extended by several investigators and the differences were confirmed. The hitherto reported studies have been concerned mainly with full-term infants and it was the purpose ...
متن کامل